Differential CD4+ cell count increase and CD4+
نویسندگان
چکیده
منابع مشابه
Differential CD4+ cell count increase and CD4+ : CD8+ ratio normalization with maraviroc compared with tenofovir.
OBJECTIVE Studies exploring the immunologic effects of maraviroc (MVC) have produced mixed results; hence, it remains unclear whether MVC has unique immunologic effects in comparison with other antiretroviral drugs. We sought to determine whether MVC has differential effects compared with tenofovir disoproxil fumarate (TDF) during initial antiretroviral therapy. DESIGN Prospective study in AI...
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INTRODUCTION Rituximab (RTX) is a B cell-depleting agent approved for the treatment of granulomatosis with polyangiitis (GPA). RTX reduces antibody producing precursor plasma cells and inhibits B and T cells interaction. Infections related to T cell immunodeficiency are not infrequent during RTX treatment. Our study investigated CD4 cell count and CD4/CD8 ratio in GPA patients during the first ...
متن کاملClinical Syndromes in HIV/AIDS according to CD4 count
Objectives: Immunodeficiency duo to HIV infection can produce unusual diseases in infected individuals & CD4 count is the main predictor of disease progression. In this study clinical syndromes resulting in admition, are considered according to CD4 count for the beter diagnosis and treatment of clinical ...
متن کاملRelationship between CD4 count and CD4% in HIV-infected people.
OBJECTIVE To describe the relationship between absolute CD4 count and CD4%, and the influence on this of gender, risk group, age, a diagnosis of AIDS, use of zidovudine (ZDV) therapy and PCP prophylaxis. METHODS 9203 paired serial measurements of CD4 count and CD4% on 1017 initially AIDS-free and ZDV-naive HIV positive patients from a London-based cohort were available for analysis. Multi-lev...
متن کاملDifferential effects of HIV viral load and CD4 count on proliferation of naive and memory CD4 and CD8 T lymphocytes.
We previously showed that HIV infection leads to expansion of a rapidly proliferating pool (s(1)) of CD4 and CD8 T lymphocytes. In the current study, we used in vivo labeling with bromodeoxyuridine to characterize the kinetics of naive, memory, and activated (HLA-DR(+)/CD38(+)) subpopulations of CD4 and CD8 T lymphocytes, and to examine the relationship between kinetic parameters and baseline C...
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ژورنال
عنوان ژورنال: AIDS
سال: 2016
ISSN: 0269-9370
DOI: 10.1097/qad.0000000000001181